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Volume 6, Issue 1 - January 18, 2007

Envirotainer, a provider of active temperature-controlled air transportation solutions for refrigerated pharmaceutical shipments.

Survey Finds Nearly Three in Four Consumers Fail to Take Medications as Directed
By David Vaczek
Senior Editor

It's unfortunate, but consumer perception can't always be trusted. A majority of consumers believe that they are highly compliant with their prescription drug regimens, yet a national telephone survey of 1000 adults reveals widespread nonadherence. The survey was sponsored by the National Community Pharmacists Association (NCPA; Alexandria, VA) and the nonprofit Pharmacists For the Protection of Patient Care (P3C).

Such findings make us wonder-could packaging play a role in keeping patients on track? Or, at the very least, could packaging alert patients to their own nonadherence so that they can take steps to remind themselves?

Sixty-four percent of the survey respondents said that they follow physicians' instructions "extremely closely." Yet the survey found that 74% of respondents admitted to some form of nonadherence.

The results point to a disconnection between consumers' beliefs and their behavior, the survey found. Officials from NCPA and P3C, joined by S. Lawrence Kocot, senior advisor to the administrator, Centers for Medicare & Medicaid Services, and J. Lyle Bootman, chairman of P3C, revealed the results in a recent press conference.

In the survey, 49% said they had forgotten to take a prescribed medication, and 31% said they did not fill a prescription they were given. Twenty-nine percent stopped taking a medication before the supply ran out. Nearly one-quarter of respondents took less than the recommended dosage. More than one in ten said they had substituted on OTC drug instead of filling the prescription, and an equal number said they had taken someone else's prescription.

"These findings are very disturbing. They suggest that patients aren't fully aware of the implications of not taking the right dose of medicine at the right time," said Bruce Roberts, NCPA's vice president and CEO.

"Even more surprising, fewer than half indicated they had consulted their doctor or pharmacist before making these changes. We are talking about much more than dollars and cents here. It's really the well being of the American public," he added.

An "overwhelming" 90% of respondents indicated they view noncompliance as a serious problem. The cost of noncompliance has been estimated at $100 billion per year, arising from factors including increased hospitalization and nursing home admissions, officials noted.

The survey demonstrated consumer confidence in pharmacists, as 68% said that pharmacists are more knowledgeable about prescription drugs than are other healthcare professionals. Two-thirds of consumers said they go to one pharmacy for their drug needs, and 86% said they would likely talk to their pharmacists about their medications.

Patient education needs to employ many channels that include caregivers, insurance companies, the Internet, written materials, and packaging that reminds patients when to take their drugs, officials said.

"What we need is a systematic approach that helps educate patients on the value of their medications and the importance of taking them exactly as prescribed, as well as one that promotes dialogue with the patient's entire healthcare team," said Ian Salditch, P3C's founder.

With scant labeling and forgettable presentation, amber vials struggle to educate-or remind-patients of anything. On the other hand, sophisticated packaging and labeling could be part of a systematic approach to better patient education. They could definitely support the education that pharmacists could provide or even substitute for pharmacists in a pinch. Think of all the product information and reminders that you could build into wallet-style or calendar-style blisters, bottles with expanded-content labeling, or even dispensers with counters. Using these sorts of tools could help patients understand-and remember-their regimens.

Read the Current
issue of PMP News

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David Vaczek
Senior Editor

Related Stories

Compliance Packaging: The Marketing Benefits of a Patient-Friendly Regimen
http://www.devicelink.com/pmpn/archive/03/06/003.html
Compliance packaging that helps patients follow drug regimens may also make a drug brand more memorable.
By Daphne Allen

Universal Solutions Sought to Address Patient Needs
http://www.devicelink.com/pmpn/archive/06/05/004.html
Any package design that leaves patients out is just decoration.
By Daphne Allen

On the Right Track
http://www.devicelink.com/pmpn/archive/05/06/001.html
Compliance packaging is making inroads into the pharmaceutical industry.
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Material of the Month

Vials for Injectables
Cyclic olefin copolymer (COC) vials for injectables feature thermoplastic elastomer (TPE) caps. The Diabolo vials and caps are manufactured in a cleanroom environment and are sterilized so that they do not require any additional processing before filling. The COC vial is filled through the TPE cap and the hole is then resealed with a laser. The concept was brought to the vial manufacturer by a filling equipment manufacturer.
Rexam Pharma, Buffalo Grove, IL; 847/541-9700; www.rexam.com/pharma.
Aseptic Technologies, Les Isnes, Belgium; +32 81 409410; www.aseptictech.com.

Machine of the Month

Blister Design Program
A CAD simulation tool and software program is designed for finite-element modeling for thermoforming pharmaceutical blister packages. Pentapharm BlisterPro is designed to improve the film selection process and provide package engineering support services to the pharmaceutical industry. It allows package designers, technicians, and engineers to explore the effects of tool geometry, film characteristics, and process conditions before running actual experiments. The program provides three stages of simulations: thickness distribution, surface area, and permeability estimates of thermoformed cavities. It is designed to evaluate barrier improvement and optimization for existing tools and films and understands cause and effect while addressing constraints.
Klöckner Pentaplast of America Inc., Gordonsville, VA; 540/832-3600; www.kpfilms.com.

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