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Volume 5, Issue 11 - October 27, 2006

Envirotainer, a provider of active temperature-controlled air transportation solutions for refrigerated pharmaceutical shipments.

Multisorb Technologies, a global manufacturer of more than 1,600 solutions to protect against moisture, oxygen, odor, and other volatiles

Dehumanizing Drug Dispensing
By Stephanie Steward
Assistant Editor

Just how common are pharmacy errors? It may be a hard question to answer. However, recent reports about such mistakes out of San Antonio, TX, paint an alarming picture. And this was just one city in one month.

KSAT.com San Antonio reported that a nine-month-old San Antonio boy was given a steroid instead of the prescribed antibiotic. He ended up in the emergency room after suffering from hyperactivity. Four days later, KSAT.com reported that a nine-year-old schizophrenic and bipolar patient was given the wrong formula of depakote. He is now at risk for liver damage. In response, Walgreen's claimed that pharmacy errors are rare. But in the Institute of Medicine (IOM)'s report, Preventing Medication Errors, the authors write that anywhere from 1.7% to 24% of prescriptions are erroneously dispensed. Even if the most recent study, which puts the error rate at 1.7%, best represents reality, it still means that 51.5 million errors are made during the filling of 3 billion prescriptions each year, the authors write.

Medication errors have been blamed on long work hours impairing the judgment of exhausted medical professionals, safety and storage procedures not being followed, and difficulty discerning between products that are similarly packaged or named. In other words, these errors are blamed on humans. The human dispensers.

Could humans be removed from the process of drug dispensing? Not entirely. But perhaps some of the responsibility could be taken off of the end-of-the-line handlers (pharmacists and nurses) and put back on creative package designers. At the very least, if most brands of gum are available in blister packs, surely more drugs could be packaged in easily identifiable, premeasured doses. We don't necessarily need a fully automated pharmacy that resembles a sterile vending machine. But perhaps we could reduce the amount of pill counting pharmacists have to do.

The IOM report made specific recommendations for healthcare organizations, federal agencies, and industry to address preventable prescription drug errors. To eliminate possible misreading of handwritten prescriptions (to finally rid the world of doctors' notorious chicken-scratches), the report recommends that "U.S. healthcare providers must move away from paper-based prescriptions to the electronic prescribing of drugs by all providers by 2010." Such a suggestion seems completely realistic considering how prolific personal digital assistants (PDAs) are among professionals anyway.

The report also suggests that FDA, the Agency for Healthcare Research and Quality, and the pharmaceutical industry should collaborate with the United States Pharmacopeia, the Institute for Safe Medication Practices, and other appropriate organizations "to develop a plan to address the problems associated with drug naming, labeling, and packaging by the end of 2007." How difficult or costly would it be for packagers and pharmaceutical companies to make sure that child and adult doses of drugs are packaged in completely and vividly different colors? Certainly nothing compared to the cost of losing lives.

These are reasonable and necessary calls for action from the industry. Healthcare professionals aren't all of a sudden going to be more rested and able to eliminate their own human tendency to err. A tired pharmacist or nurse is much more likely to choose correctly between two different sizes of dose packs than he or she is to accurately count out dozens of pills into a vial. The power to change these horrifying statistics is in the hands of packagers.

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Stephanie Steward
Assistant Editor

Related Stories

Editorial
Packagers Hold the Key
IoM discusses the problems posed by similarly named drugs and by cluttered labels and small fonts. But the problem goes well beyond labeling issues.
By Daphne Allen

Newsletter
Topical Gel Now Easier to Compound With Just One Clindamycin Vial
The nationwide pharmacist shortage, which USA Today reports peaked in 2001 with 7,700 chain pharmacy jobs open, poses the risk that overworked pharmacists will make mistakes when preparing prescriptions. Anything that pharmaceutical manufacturers and packagers can do to make pharmacists' jobs easier can help reduce that risk.
By Stephanie Steward

Editorial
Free Pharmacists with Packaging
Dug up from our archives, this editorial on overworked pharmacists still rings true.
By Daphne Allen

Material of the Month

Pearlized Ampules
A manufacturer of dispensing solutions offers a pearlized, etched version of its plastic ampule. Previous models were offered in only a natural shade of polyethylene and polypropylene blends. The pearlized version is available in a variety of colors. The manufacturer also offers raised etching on the ampules, such as the customer's name or logo. The ampule's tip is activated by gently squeezing the ampule, which ruptures the internal membrane. Another squeeze then dispenses the contents through the applicator tip. The user controls the rate and flow. James Alexander Corp., Blairstown, NJ; 908/362-9266; http://www.james-alexander.com.

Machine of the Month

Intermittent-Motion Cartoner
An intermittent-motion cartoner features a 3.8-m footprint and an output rate of up to 165 cartons per minute. The SI 10 cartoner is specifically designed for pharmaceutical applications. It features standard and custom-engineered infeed systems designed to enable components of varying sizes and shapes to be loaded into the same carton. The machine also features servo-driven technology and reproducible size changeovers. IWKA PacSystems, Fairfield, NJ; 973/227-5575; http://www.iwkapacsystems.com.

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