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Originally Published PMPN March 2001

Desiccant Tablet Helps Streamline Production

Diagnostic test kit manufacturer turns to a beveled-edge desiccant tablet to decrease line downtime.

Quidel Corp. (San Diego) is a manufacturer of a wide range of diagnostic test kits that specifically address women's health issues. Among the tests that the company manufactures are those that provide rapid diagnosis for pregnancy, strep A, influenza, chlamydia, infectious mononucleosis, and urinalysis, mostly under the Quick Vue brand name.

The kits, which are generally used in clinics, clinical laboratories, hospitals, wellness centers, and doctors' offices, are comprised of carefully engineered and packaged strips. Desiccants are required for such kits to ensure that test strips work effectively. "They keep moisture out," explains Terry Campbell, director of materials at Quidel. "These are highly moisture-sensitive tests, so we want the test strip to stay dry."

Insertion into packaging is convenient with Süd-Chemie's Tri-Sorb tablets.

Keeping the moisture-sensitivity requirements for such tests in mind, Quidel turned to Süd-Chemie Performance Packaging (Belen, NM) for a desiccant that would provide functionality while reducing production costs.

The diagnostic kits are carefully designed so that test strips are inserted into a plastic housing, with the Tri-Sorb desiccant tablets placed into a special compartment within the plastic. "The product's design, which discreetly and automatically places the desiccant into the housing, eliminated much of the inefficiency," Campbell says.

The production line at Quidel has little downtime. This was not always the case. Campbell attributes much of the company's increase in profits to improved production efficiency. "When we switched to Tri-Sorb tablets, we began to see additional returns and steadily decreased downtime. Time spent cleaning desiccant chips and dust out of our machines was virtually eliminated," says Campbell.

Tri-Sorb tablets' beveled edges have helped Quidel reach its downtime goal. The beveled edges work well with automated insertion machinery. The custom design allows for quick and easy insertion into packaging without chipping and without jamming the equipment.

In addition, the tablets' high capacity for water adsorption has helped reduce downtime. Tri-Sorb molecular sieves originate from zeolite compounds, which are used for adsorption. Adsorption occurs when moisture is held inside a desiccant by physical bonds; no chemical change actually occurs. The tablets adsorb water molecules easily because they possess a high degree of polarity and have the proper molecular size for entrance into sieve pores. They have a uniform pore structure that enables them to separate molecules by size.

Campbell reports that Tri-Sorb tablets have been incorporated into all Quidel kits that require desiccants. "At this point, it's a standard part of the kits. The tablets work well protecting against moisture. Kits also have longer shelf lives," he says.

Now that the company uses the tablets the amount of time the production line runs each year has been decreased by 15%, while overall production has increased, explains Campbell. "This means less wear and tear on the machinery and lower labor costs." He adds that the tablets weigh less than the previously used desiccants, which makes the diagnostic kits lighter and decreases shipping costs.

Campbell also notes, "Just-in-time delivery of consistent-quality tablets from Süd-Chemie not only keeps our lines running but also helps us reduce inventory costs. Süd-Chemie stocks a warehouse filled with custom-made inventory. We forward a purchase order, and it's filled within 10 days."

Copyright ©2001 Pharmaceutical & Medical Packaging News