Company

Brand name(s)

Product focus

Product status

Regulatory approvals

Company status/revenue

Adlyfe Inc.

N/A

Neurodiagnostics for the detection of Amyloid diseases, including Alzheimer's and Parkinson’s

Clinical development

Not yet applied

Development stage

Apnex Medical

Hypoglossal nerve stimulation therapy device

Implantable medical device for the treatment of obstructive sleep apnea

Clinical trials planned for 2009; commercialization by 2012

N/A

Development stage

Brainsway Inc.

Transcanial magnetic stimulation device
Noninvasive device for treating depression, schizophrenia, autism, bipolar, and other disorders
Clinical trials
N/A
Development stage

Brainscope Co., Inc.

BrainScope NT-1000
Hand-held mobile devices that quickly assess brain function at the initial point of care
Clinical trials
FDA approval expected 3Q08
Development stage

CoAxia Inc.

NeuroFlo catheter
Balloon catheter device to increase cerebral perfusion to minimize damage from ischemic stroke or vasospasm
Clinical trials
HDE
Development stage

EnteroMedics Inc.

Maestro VBLOC system
Neuro blocking for obesity
Investigational
IDE
Development stage

Envoy Medical Corp.

Esteem hearing implant
Implant for treatment of sensorineural hearing loss
Investigational
IDE; CE mark
Not disclosed

Intelect Medical Inc.

N/A
Deep-brain stimulation implant
Preclinical studies
IDE
Development stage

Neuronetics Inc.

NeuroStar TMS therapy system
Transcranial magnetic stimulation for treatment of depression
Clinical trials
IDE; full FDA approval before 1/09
Development stage

NeuroPace Inc.

Responsive Neurostimulator system
Neurostimulation device for the treatment of epilepsy
Clinical trials
IDE
Development stage

NeuroVista Corp

N/A
Early-warning system for epileptics
Research and development
N/A
Development stage

Northstar Neuroscience Inc.

Renova cortical stimulation system
Neuromodulation for depression
Clinical trials
IDE
Development stage

Omneuron Inc.

N/A
Real-time functional MRI technology
Current clinical trials on smoking cessation and chronic pain
Not yet applied
Development stage

Synapse Biomedical Inc.

NeuRx diaphragm pacing stimulation system
Neuromodulation for chronic respiratory insufficiency
Marketing to selected European centers
CE mark (12/07); HDE pending
Not disclosed

Victhom Human Bionics Inc.

Power Knee, Neurostep
Neurobionic prostheses
Marketing to selected European centers
Clinical trials in United States
$2.27 million (FY 2007)
Table II. Product focus and status for early-stage neurotechnology companies.