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Originally Published MX November/December 2001

BUSINESS PLANNING & TECHNOLOGY DEVELOPMENT

Hot Spots: 10 Sites for the Medtech Executive’s Itinerary

Communities throughout the country are wooing medtech companies. Here are 10 of the most notable.

Cliff Henke

Medical technology has always been one of the star attractions of economic development agencies throughout the world, and those in the United States have not been immune to its luster. As the world appeared to be already dipping into recession well before the outrages of September 11, such agencies are stepping up their efforts to lure companies in this sector.

However, medtech companies and their investors can be hard to convince. The complexity of the industry and its finances means that regional development agencies have to work doubly hard to offer medtech executives just what their companies are looking for.

According to Daniel Wood, a partner with the venture capital (VC) firm IngleWood Ventures (San Diego), "Location is still very important. Virtual companies can’t offer the employee-management synergies, with face-to-face, instantaneous contact, offered by traditional companies."

In Wood’s view, the main factors to consider in evaluating a region’s potential to attract medtech firms are "the quality of employees and management and the availability of venture capital" in an area—especially in the case of private, early-growth-stage companies.

What about the importance of a technology base? According to Wood, communities no longer need to build a critical mass of companies in order to reach hotbed status, because in today’s wired world the ideas and technology edge lure both the money and people to them, wherever they may be. "Having the right people and technology tends to attract venture capitalists," he says.

When it comes to the preferences of such VCs, however, Wood admits that location can be a key factor. "VCs typically wish to invest as close to home as possible, particularly with early-stage companies." Whether they have an emotional or intellectual stake in their protégé’s success, or just want to keep a close eye on their money, the usually high-risk nature of the venture-capital deal means that VCs want contact.

While there are many more successes than listed here, the 10 regions discussed below illustrate certain themes that have resonated with medtech companies. By no means a 10-best list, the sites are arranged alphabetically.

1. Austin, Texas: Medtech Joins High-Tech

The convergence of money, technology assets, and people make Austin a fast-growing medtech hotbed. According to Susan M. Davenport, director of economic development at the Greater Austin Chamber of Commerce, the region’s academic institutions have strengths in computer science that have helped spur several start-ups in the emerging genomics field. "In so much of genomics and biotechnology, as well as pure bioinformatics products and services, there is a very strong emphasis in computer science and software engineering. The Austin area has a strong tradition in these areas," she says.

In addition, the University of Texas (UT), which is based in Austin, boasts the number two pharmacy school in the country. Moreover, the MD Anderson Medical Center (Houston) is the university’s teaching hospital, and both institutions have spawned numerous companies and products based on research conducted there.

However, in their economic development plans, business and academic leaders are choosing to emphasize interdisciplinary collaboration and greater technology focus, says Davenport. "This is because so many medical products are now technology based."

To this end, UT has recently formed a Center for Nanotechnology and Biology, designed to bring previously separate academic fields together in a single place in order to foster collaboration. In addition it has founded a Center for Computational Science and Bioinformatics, bringing together researchers and professors from computer science and biology for the same reasons.

2. Boston: Will Route 128 Surpass Silicon Valley?

Boston has been a national leader in medtech development for many years. That leadership is expected to continue, as the region’s critical mass of existing medtech companies, growing labor pool supplied by world-class academic institutions, and depth of investment and technology resources show no sign of faltering any time soon.

The Boston area already boasts nearly 600 medtech enterprises combining for more than $8.3 billion in annual sales, according to U.S. Department of Commerce data. These organizations employ more than 35,000 people and are contributing an increasingly important share of the regional economy, particularly as a source of high-wage jobs.

Officials in Boston constantly compare their medtech economic strength with that of Silicon Valley—but they insist that they are not in competition. Rather, they note, many Boston-area companies are involved with cutting-edge collaborative research projects with Silicon Valley companies. Researchers of the Whitehead Institute at the Massachusetts Institute of Technology, for example, have collaborated with San Francisco firms Hyseq and Affymetrix, two manufacturers of microarray chips, in genomics research.

3. Florida’s High-Tech Corridor

The outlook for the medical technology industry in Florida is characterized by strong growth, a very healthy export market, and high value-added manufacturing. The demands of Florida’s own healthcare market—fueled by the continued influx of retirees from the rest of a graying America as well as one of the fastest immigration rates anywhere —are certainly among the critical drivers of this growth.

Florida’s medtech industry employs 49,300 workers in nearly 2000 businesses. When combined with the state’s healthcare services providers, the sector’s employment totals more than 261,000 in more than 2100 firms, ranking the state second in the nation.

Another key factor in Florida’s rosy outlook is that the Sunshine State is one of the Western Hemisphere’s great commercial crossroads. Total exports of Florida’s biomedical manufactured products increased from $1.6 billion in 1993 to $1.9 billion in 1997, according to state government data.

"Although biomedical technology firms can be found in all regions of the state, they tend to cluster in or near communities that have a substantial scientific and academic presence," says Ann Patrick, marketing director for Enterprise Florida Inc. (Orlando).

4. Kansas City, Missouri: The Heartland of Medtech Research

Situated near the nation’s geographic center, Kansas has long thought of itself as the heart of America. Now, the state’s namesake city—the one across the river in Missouri—is aiming to capture some of that glory by becoming at least one of the major arteries in the nation’s life sciences research community. The reason is simple: many officials and business leaders see medtech growth in the region as key to the economic survival of Kansas City, which has been rocked in recent decades by the steadily worsening Farm Belt crisis.

There are several aspects to their strategy. First, they have developed the KCCatalyst, a strategic plan for promoting the technology community in the Kansas City area. The plan is intended to better coordinate and monitor the activities of technology companies, academic and research institutes, and financial and professional services in the region.

In addition, the Kansas City Life Sciences Institute was formed to combine six local medical and research facilities in order to make their work more effective and attractive to outside investors. Two wealthy Kansas City cancer survivors established an endowment of more than $515 million to found the institute, and they and the institute’s leadership hope to attract another half-billion dollars annually to its work. The institute has identified five areas for advanced studies: cancer, human development and aging, cardiovascular disease, infectious disease, and neurological disease. Its overall objective is for the region’s annual biomedical R&D expenditures to expand from $100 million to $500 million.

5. Montgomery County, Maryland: DNA Alley

Stretching along 15 miles of Interstate 270 from Bethesda to Gaithersburg in Montgomery County, MD, is the so-called DNA Alley. Thanks to breakthroughs in genomics and bioinformatics by companies headquartered there, this county in the suburbs outside Baltimore and Washington, DC, has become the anchor of the nation’s third-largest biotech community.

Home to some 200 medtech establishments, the county’s phone directory is a who’s who of those involved with genetic research, including Celera, Human Genome Sciences, Gene Logic, Origene, and the Institute for Genomic Research.

None of this is an accident. Montgomery County is also home to the National Institutes of Health and FDA. Thus, the county has one of the largest pools of scientists and engineers in the nation. Indeed, many who left to start or join DNA Alley’s many companies are former employees of these federal agencies.

Other federal establishments that have synergies with medtech fields include NASA’s Goddard Space Flight Center (Greenbelt) which developed the Hubble space telescope and thus possesses unique capabilities in imaging and optical technologies; and the National Security Agency (Fort Meade), which has some of the most sophisticated informatics technology in the world. Supplying a steady influx to the talent pool is the large cluster of prestigious colleges and universities located within a half-hour drive of Montgomery County.

6. New Mexico: Techno-Oasis

It probably shouldn’t be surprising that New Mexico is ranked second among the 50 states for the most doctorate-level scientists and engineers per capita. After all, the state is home to the Sandia and Los Alamos National Laboratories, which became known throughout the world for their nuclear weapons research, but in recent years have emphasized their capabilities in a variety of fields with more civilian uses. Three growing research universities and three developing research parks add to New Mexico’s high-tech credentials. The state ranks near the top in the nation in total R&D expenditures (per $1000 of gross state product).

Other public-sector research facilities include the University of New Mexico–based Institute of Advanced Microelectronics, which was established under the aegis of the Microelectronics Research Center created by NASA in 1995. Potential commercial applications of its research include data storage, medical diagnostics, telemedicine, surgical instrumentation, and communications.

There are nongovernmental research institutions located in New Mexico as well. For example, the Santa Fe–based nonprofit National Center for Genome Resources (NCGR) is conducting nationally recognized work in the industry. NCGR creates biological databases and analytical tools to accelerate and enable discovery through genomic research.

Among New Mexico’s 900-plus high-tech companies are those in microelectronics, information technology, optoelectronics, medical technology, and advanced materials. Of those, more than 90 are medtech businesses.

Recognizing the role of money in attracting medtech firms, New Mexico plans to invest more than $161 million in state funds to be used as seed money with resident venture capital firms. But state funding is merely a drop in the bucket. Since 1997, New Mexico has seen a 900% growth rate in resident venture capital firms, with total capital invested by these firms reaching nearly half a billion dollars.

7. Silicon Valley, California

Think of a place for high-tech innovation and it’s almost impossible to miss Silicon Valley, the stretch of Northern California running from San Francisco to San Jose. Not only is it the cradle of the computer age, it is home to a long list of medtech firms, ranging from Hewlett-Packard’s businesses in clinical laboratory equipment and medical imaging, to manufacturers of so-called DNA chips, the new microarray technologies that make large-scale gene-hunting projects possible. Indeed, a glance at the roster of any area venture capital firm reveals that life sciences companies are among the handful of industrial sectors these investors consistently target.

Combine the financial muscle and anything-is-possible entrepreneurial attitude of Silicon Valley—though daunted by the dot-com implosion—with the formidable intellectual assets of Stanford University, the University of California at Berkeley (still boasting the largest number of faculty with Nobel laureates of any public education institution in America), and the Lawrence Berkeley and Lawrence Livermore National Laboratories (not to mention the Ames Research Laboratory of NASA), and Silicon Valley will remain a force to reckon with for many years to come.

8. Southern California: The Tech Coast?

Up and down the length of the Tech Coast that runs from Santa Barbara to San Diego, business groups and local governments alike are letting it be known that the region is a hotbed of medtech development. Virtually every market in medical devices and biotechnology has a major company that hails from Southern California, ranging from Beckman Coulter in Orange County; to Baxter Pharmaseal, Siemens Pacesetter, and Minimed in Los Angeles County; to biotech giant Amgen in Ventura County.

The area’s venture capital and financial muscle is enviable. According to data compiled by VentureOne and PriceWaterhouseCoopers, no fewer than 20 financings in biopharmaceuticals and an equal number in medical devices worth more than half a billion dollars were concluded in Southern California during the first half of 2001 alone. The region also has a wealth of scientific resources, including the University of Southern California and the University of California campuses at Los Angeles and Irvine, which have world-class biomedical research programs and facilities. In addition, prodigious technology transfer opportunities are available via NASA’s Jet Propulsion Laboratory (Pasadena), which is operated by Caltech.

Yet many prominent business leaders and public officials in the region believe that too few people outside Southern California know these facts—and that too many view the region as second fiddle to Silicon Valley. Other challenges include high marginal tax rates; increasing energy, labor, and land costs; and a general attitude of unhelpfulness among certain governmental agencies, particularly compared with neighboring states. Then there is another problem: getting a hearing with investors whose attention is often drawn away by the glamour of Hollywood.

9. Twin Cities: The Alley as Avenue

The confluence of world-class healthcare research and academic institutions, plus ample access to a skilled labor pool and synergies with similar companies, continues to give credence to the nickname bestowed on the corridor stretching between Rochester and the Twin Cities area in Minnesota: Medical Alley. While the Mayo Clinic (Rochester) is perhaps the best-known medical facility in the world, the University of Minnesota is one of the top universities in the country when ranked by the number of patents generated by its esteemed faculty and staff.

According to FDA figures, there are about 800 registered medical device firms in Minnesota, an increase of almost 40% since 1994. More than 65 new medical device manufacturers were established in the state between 1990 and 1998—an increase of 45%—making the Gopher State one of the top five in this category nationally.

In the field of cardiology, Guidant Corp., Medtronic, and St. Jude Medical are headquartered there. The huge Minnesota conglomerate 3M has a major healthcare presence; its surgical drapes and biomaterials are just two product lines in which the company is a world leader in market share.

10. Utah: Beehive of Medtech

Make no mistake: Utah is one of the regions that is looking to attract medtech and other high-technology companies away from the traditional locations for these industries. Last year, the Economic Development Corporation of Utah (EDCU) released a study evaluating the competitive position of Utah’s metropolitan areas over other high-technology locations, including Silicon Valley.

In the wake of last year’s report, Governor Mike Leavitt and other leaders created the Utah Technology Alliance to jointly target Silicon Valley companies and try to attract them to the Beehive State. To accomplish this task, the alliance is focusing on two main goals: provide an attractive location for high-technology firms and create a business- and capital-friendly environment.

The state boasts a lower-cost, well-educated, and healthy workforce, which has been attractive to medtech companies, says Kim Scott, director of marketing and communication for EDCU. Other assets include the region’s history of success in the fields of computer science, which can help attract firms in the fields of bioinformatics and genomics.

Conclusion

Whether trying to emulate the Silicon Valley model or compete with it, all the above regions of the country share one characteristic: they intensely want medtech companies to locate there. The combination of low-polluting, high-wage, and high-growth facets of most of the companies they are attempting to woo are themselves too great a lure not to try.

Cliff Henke is a freelance writer based in Southern California.

Copyright ©2001 MX