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Table II. A sampling of time-temperature relationships for steam sterilization.
Sterilizing Plastic
Steam Sterilizing Response
Radiation Sterilizing Response
Ethylene Oxide Sterilizing Response
Dry Heat Sterilizing Response
AcetalGoodNoGoodGood
AcrylicPoorGoodGood
Acrylonitrile butadiene styreneVariesaGoodVaries
High-density polyethyleneGoodGoodGood
NylonVariesaGoodGoodNo
PolycarbonateVariesGoodGoodGood
PolyesterPoorGoodGood
PolyethylenePooraGoodGood
Polyglycolic acidNoNoGood
Polymethyl penteneGoodPoorGoodOK, no load
PolypropyleneGoodVariesGoodOK, no load
Polypropylene and polyethylene copolymerGoodGoodGoodOK, no load
PolystyrenePoorGoodGood
PolysulfoneGoodGoodGoodYes
PolyurethanePoorGoodGood
Polyvinyl chlorideVariesaVariesGood
Polyvinylidene fluorideGoodGoodGood
SiliconeGoodGoodGoodLow temp.
TeflonVariesNoGoodOK
a There are many materials that can be damaged by high-temperature heat, including acrylonitrile butadiene styrene, acrylic, styrene, low-density polyethylene, polyvinyl chloride, etc.; however, acetal, polypropylene, and Teflon could be possible candidates for heat because these materials can be damaged by radiation. Polyurethane may be hydrolytically attacked by steam but not by low-temperature dry heat, EtO, or radiation. Material compatibility and considerations need to be evaluated before accepting any sterilization method listed above. See Table III for other possible candidates.