Manufacturing and Processing Technologies
Fabrication of sensor arrays requires reagent-dispensing that can deliver volumes ranging from
the low microliters to picoliters. Such dispensing systems must be compatible with variousreagents, including organic solvents, biological fluids, polymeric solutions, and combinations of these.
These systems must be robust and capable of producing hundreds of thousands to millions of dispenses with high precision and accuracy. This article reviews process parameters that affect higher reproducibility as measured by coefficient of variability and better efficiency for high
volume manufacturing.

Optically Stimulated Piezofilm Immunoassay
Optically-stimulated piezofilm detection is a new nonseparation immunoassay method.
The detection method relies on heat being generated in a sample upon illumination, with this
heat then causing stress at the surface of a piezoelectric polymer. This stress generates a charge that is directly proportional to the amount of reporter antibody bound at the piezofilm surface.
The simplicity of the technology makes it ideal for point-of-care immunoassay applications.

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