Implant Sciences Corp.
Implant Sciences Corp. develops products and surface treatment technologies to the medical device industry using ion implantation and thin-film coatings of radioactive and non-radioactive materials. Products and surface treatments include: devices for radioactive therapy; ion implantation and ion-beam texturing; and MicrofusedTM coatings, such as ceramic coatings for orthopedic implants, ceramic coatings for insulating medical devices, scratch-resistant hard coatings for orthodontic applications, and radiopaque coatings for intervascular devices. The company's modern facility incorporates state-of-the-art research and production facilities and Class 100 cleanrooms.
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Implant Sciences Corp.
107 Audubon Rd., Ste. 5
Wakefield, MA 01880-1246
Tel: 781/246-0700
Fax: 781/246-1167
Web: http://www.implantsciences.com
E-mail: info@implantsciences.com
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IMPLANT SCIENCES CORPORATION
Implant Sciences Corporation develops products and surface treatment technologies to the medical device industry using ion implantation and thin-film coatings of radioactive and non-radioactive materials. Products and surface treatments include: devices for radioactive therapy; ion implantation and ion-beam texturing; and MicrofusedTM coatings, such as ceramic coatings for orthopedic implants, ceramic coatings for insulating medical devices, scratch-resistant hard coatings for orthodontic applications, and radiopaque coatings for intervascular devices. The company's modern facility incorporates state-of-the-art research and production facilities and Class 100 cleanrooms.
SURFACE MODIFICATION BY ION IMPLANTATION
Ion implantation is an advanced surface treatment that enhances the performance of a surface. Implantation is used to enhance mechanical and chemical surface properties without altering the bulk properties of a material. Characteristics such as lubricity, wettability, surface hardness, corrosion resistance and overall wear resistance can be improved using ion implantation. Current applications include increased fretting resistance of titanium tapers and decreased polyethylene wear debris formation against cobalt-chromium bearing surfaces in orthopedics, and reduced thrombus formation on various polymer surfaces in intervascular applications.
RADIOACTIVE ION IMPLANTATION
Implant Sciences has developed a safe and effective process for implanting a variety of beta, gamma, and x-ray emitting ions into medical devices. The company has radioactive coronary stents and interventional cardiology devices for the prevention of restenosis (reclosure of the artery after balloon angioplasty) currently under development. Radiation delivered by stents or catheters is known to be a potential inhibitor of restenosis in the cardiovascular system. The company has received Food and Drug Administration 510(k) clearance to market its I-PlantTM Iodine 125 radioactive seed for the treatment of prostate cancer. Seeds for delivering radiation to the prostate are considered to be an effective means of treatment for early stage prostate cancer.
MICROFUSIONTM ... MORE THAN A COATING
Applying metal or ceramic coatings to medical devices requires a process that ensures against the possibility of the film separating from the surface of the device. Implant Sciences' proprietary Microfusion technology utilizes a simultaneous ion bombard to couple energy into the growing coating. The result is a dense, extremely well adhered coating.
MICROFUSEDTM RADIOPAQUE COATINGS
Radiopaque coatings are applied to medical devices as markers eliminating the need for crimping or swaging hard, inflexible metal rings. The proprietary coating absorbs x-rays, making treated 
catheters, stents, guidewires, and other devices easily visible with fluoroscopy.
MICROFUSEDTM HARD, INERT COATINGS FOR TITANIUM ALLOYS
The use of titanium alloys (including super-alloys) has been hindered because of titanium's lack of hardness and tendency to gall. The affect of these poor surface qualities can be eliminated with the use our proprietary (patent pending) low friction coating. The coating significantly increases surface hardness while reducing friction and stick-slip motion even under loading. Applications include orthodontic archwires, spinal and dental implants.
MICROFUSEDTM CERAMIC COATINGS
Coatings of alumina or zirconia can be deposited using ISC's patented ion beam synthesis technique to grow these ceramics into and on a surface. The coating has a graded interface that transitions from the metal substrate to a 100% fully stoichiometric ceramic coating. The "coating" cannot delaminate since it is integrated into the underlying structure. This technology enables for the first time, a composite metallic-ceramic device.
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