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INDUSTRY NEWS

Recently introduced testing services from CSMA include delivery system research, cleanliness validation, and process evaluation.

A comprehensive package of testing services for manufacturers of medical inhalers has been introduced by the Centre for Surface and Materials Analysis (CSMA; Penkhull, Staffs, UK). The array of services includes delivery system research, cleanliness validation, and process evaluation.

The company uses powerful time-of-flight secondary ion mass spectrometry (ToF-SIMS) imaging technology to inspect inhalers. This allows technicians to map the distribution of active drugs on excipient carriers. The resulting information can be used to develop efficient drug-delivery mechanisms, according to CSMA marketing manager Shaun Bainbridge. “The bismuth cluster source we use for this particular type of work provides the highest sensitivity levels [currently] possible,” he adds.

CSMA’s cleanliness validation services leverage x-ray photoelectron spectroscopy surface analysis techniques, which enable quantification of contaminants that may affect the cleanliness of inhaler parts.

Manufacturing and supply chain issues that may have a negative impact on the inhaler can also be evaluated. This includes potential packaging problems and the effectiveness of surface treatments.

To find out more, contact CSMA, Queens Road, Penkhull, Staffs ST4 7LQ, UK; phone: +44 1782 764 269; fax: +44 1782 412 331; e-mail: enquiries@csma.ltd.uk; Internet: www.csma.ltd.uk.