Originally Published EMDM September 2002
PRODUCT UPDATE
BioInteractions Ltd.
A combination of nonthrombogenic and antithrombogenic properties on the same polymer backbone is achieved by a coating for devices such as the Trillium oxygenator (pictured) from Medtronic. The Trillium Biosurface coating, developed by BioInteractions Ltd. (Reading, Berks, UK), works on two different steps in the surface-treatment process. "The nonthrombogenic component acts on the initial stage, where protein absorption is prevented or reduced, whereas heparin, the antithrombogenic component, mainly interacts at the end of the intrinsic pathway," explains managing director Ajay Luthra. The dual nature of the coating makes it suited for bypass circuits, stents, stent grafts, heart valves, catheters, balloons, guidewires, implantable ports, vascular grafts, minimally invasive bypass devices, cardiothoracic surgery devices, sensors, and drug-delivery devices.
The company also offers solvent and aqueous-based coatings that can be applied using conventional methods such as dipping or spraying. The product range includes nonthrombogenic, lubricious, antimicrobial, drug-delivery, and heparin-based coatings.
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